Development of self-soluble intravascular implants

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LLC Innovative Company Modern Technologies is a part of the nuclear innovation cluster in Dimitrovgrad, Ulyanovsk Region.

The company focuses on the development and production of intravascular implants.

The project organizes the production of two products from self-soluble polymers:

Self-soluble cava filters are designed to prevent pulmonary embolism. They are implanted into the lumen of the inferior vena cava to trap blood clots carrying blood. Kava-filter freely passes blood, but creates an obstacle for blood clots. The created device is aimed at preventing pulmonary thromboembolism and improving the existing analogues of the cava filter device.

A classic stent is a cylindrical wire structure that serves as a skeleton for a section of an artery. During stent implantation, a durable artificial coronary artery is formed, which squeezes atherosclerotic plaque and intima fragments to its wall. The device will have the appearance of a woven cylindrical shape of a structure made of a combined soluble material, which will allow not only to maintain the reference properties, but also in the future will be a matrix for stem cells. Studies conducted in the USA, Japan and Russia have confirmed the success of using stents from soluble materials. The lumen of the vessels after the application of these devices is increased by 18% compared with the diameter of the artery during stenting.

The advantages of devices over analogues are achieved through the use of self-soluble materials:

  1. eliminates the possibility of perforation of vessels when installing devices;
  2. the effect of epithelization on the implant removal process is eliminated;
  3. additional surgical interventions during the migration of filters and stents are excluded;
  4. indications for the implantation of intravascular implants are expanding.

Become a matrix for stem cells. Studies conducted in the USA, Japan and Russia have confirmed the success of using stents from soluble materials. The lumen of the vessels after the application of these devices is increased by 18% compared with the diameter of the artery during stenting. The advantages of devices over analogues are achieved through the use of self-soluble materials:

  1. eliminates the possibility of perforation of vessels when installing devices;
  2. the effect of epithelization on the implant removal process is eliminated;
  3. additional surgical interventions during the migration of filters and stents are excluded;
  4. indications for the implantation of intravascular implants are expanding.

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